pentobarbital will decrease the extent or effect of aripiprazole by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Monitor.
pentobarbital will reduce the level or result of estrogens esterified by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check.
pentobarbital increases toxicity of ifosfamide by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor. CYP3A4 inducers may well enhance the metabolism of ifosfamide to its Energetic alkylating metabolites.
pentobarbital will lessen the extent or effect of fesoterodine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.
pentobarbital will minimize the extent or outcome of fosphenytoin by affecting hepatic enzyme CYP2C9/10 metabolism. Use Warning/Keep track of.
Prolonged or repeated exposure could end in unfavorable effects on fetal or young young children’s Mind enhancement
Either improves toxicity of the other by pharmacodynamic synergism. Keep away from or Use Alternate Drug. Profound sedation, respiratory depression, coma, and Dying may possibly outcome if coadministered. Reserve concomitant prescribing of such drugs in individuals for whom other treatment method choices are insufficient. Restrict dosages and durations for the minimum amount essential. Monitor carefully for signs of respiratory melancholy and sedation.
pentobarbital raises toxicity of methoxyflurane by growing metabolism. Contraindicated. Elevated metabolism of methoxyflurane to nephrotoxic compounds.
To reduce the opportunity of overdosage or the development of dependence, Restrict the prescribing and dispensing of sedative-hypnotic barbiturates, to the quantity required for that interval till the subsequent appointment
This drug may possibly interfere with the absorption of orally administered griseofulvin, lowering its blood degrees; effects of blood amount reduction unfamiliar; preferable to stop concomitant administration of these drugs
pentobarbital will decrease the extent or effect of tamoxifen by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor.
pentobarbital will decrease the level or outcome of norgestrel by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Monitor Carefully. Average CYP3A4 inducers might lessen progestin focus; contemplate usage of extra barrier procedures
pentobarbital will decrease the extent or effect of ketoconazole by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Small/Importance Unidentified.
pentobarbital will lessen the level or impact of fostemsavir website by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated.